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Nanomedical materials for delivering hydrogen is a method that uses nanomaterials as carriers to effectively deliver hydrogen to the human body and realize the prevention and treatment of diseases. Hydrogen is a kind of small molecule gas with antioxidant, anti-inflammatory, anti-apoptotic and other biological effects. It can enter the human body through inhalation, drinking and injection, and has protective and therapeutic effects on a variety of diseases such as ischemic stroke, myocardial infarction, diabetes, tumor and so on. Nanomedical materials are a kind of medical materials with nanoscale, which can realize efficient load and controllable release of hydrogen by adjusting its morphology, size and surface properties, and improve the stability, biocompatibility and targeting of hydrogen, thus enhancing its biological effect.

A nano-medical material based on metal organic frame (MOF) for delivering hydrogen uses the high specific surface area and porous structure of MOF to load a large amount of hydrogen, and realizes the controlled release of hydrogen through pH or temperature stimulation. The material can enter the human body through intravenous injection or oral injection, and has protective and therapeutic effects on ischemic stroke and myocardial infarction.

A nano-medical material based on polyethylene glycol (PEG) modified carbon nanotubes (CNT) delivering hydrogen, using the hollow structure and high strength of CNT, load a large amount of hydrogen, and achieve controlled release of hydrogen through light or ultrasonic stimulation. The material can enter the human body through intravenous injection or subcutaneous injection, and has inhibitory and killing effects on tumor cells.

A nano-medical material for delivering hydrogen based on gold nanoparticles (AuNP) modified by polyethylene glycol (PEG), using the surface plasmon resonance effect and catalytic properties of AuNP to load a small amount of hydrogen and achieve controlled release of hydrogen through stimulation such as illumination or hydrolysis. The material can enter the human body through intravenous injection or oral injection, and has protective and therapeutic effects for inflammatory intestinal diseases.

Reference Documentation:

[1]A hydrogen strategy for a climate-neutral Europe, COM(2020) 301

[2]Jing Qi, Tianli Wu, Mengyao Xu, Zhubing Xiao. Hierarchical Assembly of CNTs-VSe2-VOx/S for Flexible Lithium–Sulfur Batteries. ACS Applied Materials & Interfaces 2021, 13 (33) , 39186-39194. https://doi.org/10.1021/acsami.1c07204.